Viral discovery/biology
Janowski Lab
Andrew Janowski, MD, MSCI
The COVID-19 pandemic will not be the last pandemic, as human populations will remain susceptible to newly emerging viruses. While the techniques for viral discovery have greatly expanded the number of known viral sequences, many fundamental questions regarding the biology of viruses can only be addressed through isolation and propagation of viruses in the laboratory setting.
Storch Lab
Gregory A. Storch, MD
Gregory Storch's research program is devoted to using molecular methods to improve the rapid diagnosis of infections. The infectious agents of choice are those for which existing methods are inadequate, either because the agent cannot be cultivated or because current diagnostic methods are too slow or insufficiently sensitive. The emphasis is on viral and other unconventional agents, in both normal and immunocompromised hosts. He is also interested in pathogen discovery and applications of high-throughput nucleotide sequencing to that process. Storch's main current research project is a study of viral causes of fever without focus in young children. He also continues to work on developing and evaluating new molecular diagnostic tests.
Wylie Lab
Kristine Wylie, PhD
The Wylie Lab studies the microbiome, microbial infections, and maternal host response during pregnancy. We have particular interest in the human virome, and we are interested in developing and applying innovative technologies for the study of viral communities, viral dynamics, and host response. We are carrying out in vitro studies to understand herpesvirus and papillomavirus infections during pregnancy. We use microbial genomics, in vitro cell culture, and animal models in our work.