Storch Lab

My research interests relate to the molecular diagnosis of infectious diseases. Within our diagnostic virology laboratory, we have developed molecular tests for the detection of multiple infectious disease agents, including all known human herpes viruses, polyoma viruses JC and BK, parvovirus B19, enteroviruses, HIV, Toxoplasma gondii, Bordetella pertussis and parapertussis, Ehrlichia, Rickettsia, Bartonella, Leptospira, Borrelia, Mycoplasma pneumoniae, and Chlamydia pneumoniae. Development of quantitative assays is an area of special interest, and quantitative assays for CMV, EBV, HHV-6, and BK virus have been developed. We have also implemented commercial tests for HIV RNA, hepatitis C RNA, hepatitis C genotyping, hepatitis B DNA, and have developed molecular tests for the detection of resistance of human cytomegalovirus and hepatitis B virus to antiviral drugs. Finally, we have also developed tests to detect specific forms of bacterial antibiotic resistance to antibiotics including methicillin, the fluoroquinolones, and the macrolides. This effort also includes assays to characterize the SCCmec cassette of MRSA strains and to detect the presence of the Panton-Valentine leukocidin.

Resources

• Project ARK

Principal investigator

Gregory A. Storch, MD

Ruth L. Siteman Professor of Pediatrics
Research Integrity Officer

• Phone: 314-454-6050
• Email: storch@wustl.edu

Recent publications

• Auto-inflammation and auto-immunity pathways are associated with emergence of BOS in pediatric lung transplantation
  June 1, 2022
  Auto-inflammation and auto-immunity pathways are associated with emergence of BOS in pediatric lung transplantationConrad, C. K., Hedlin, H., Chin, H., Hayes, D., Heeger, P. S., Faro, A., Goldfarb, S., Melicoff-Portillo, E., Thalachallour, M., Odim, J., Schecter, M., Storch, G. A., Visner, G. A., Williams, N. M., Kesler, K., Danziger-Isakov, L. & Sweet, S. C., Jun 2022, In: Pediatric transplantation. 26, 4, e14247.Research output: Contribution to journal › Article › peer-review
• Erratum to Efficacy of a Single Administration of 5% Povidone-Iodine in the Treatment of Adenoviral Conjunctivitis. Am J Ophthalmol 2021;231:28-38 (American Journal of Ophthalmology (2021) 231 (28–38), (S0002939421003111), (10.1016/j.ajo.2021.05.018))
  March 1, 2022
  Erratum to Efficacy of a Single Administration of 5% Povidone-Iodine in the Treatment of Adenoviral Conjunctivitis. Am J Ophthalmol 2021;231:28-38 (American Journal of Ophthalmology (2021) 231 (28–38), (S0002939421003111), (10.1016/j.ajo.2021.05.018))THAN, TAMMY., MORETTIN, CHRISTINA. E., HARTHAN, JENNIFER. S., HARTWICK, ANDREW. T. E., HUECKER, JULIA. B., JOHNSON, SPENCER. D., MIGNECO, MARY. K., SHORTER, ELLEN., WHITESIDE, MEREDITH., MARGOLIS, MATHEW. S., OLSON, CHRISTIAN. K., ALFEREZ, CHRISTOPHER. S., ZYL, TAVÉ. VAN., RODIC-POLIC, BOJANA., STORCH, GREGORY. A. & GORDON, MAE. O., Mar 2022, In: American journal of ophthalmology. 235, p. 345 1 p.Research output: Contribution to journal › Comment/debate
• CTOTC-08: A multicenter randomized controlled trial of rituximab induction to reduce antibody development and improve outcomes in pediatric lung transplant recipients
  January 1, 2022
  CTOTC-08: A multicenter randomized controlled trial of rituximab induction to reduce antibody development and improve outcomes in pediatric lung transplant recipientsSweet, S. C., Armstrong, B., Blatter, J., Chin, H., Conrad, C., Goldfarb, S., Hayes, D., Heeger, P. S., Lyou, V., Melicoff-Portillo, E., Mohanakumar, T., Odim, J., Ravichandran, R., Schecter, M., Storch, G. A., Visner, G., Williams, N. M. & Danziger-Isakov, L., Jan 2022, In: American Journal of Transplantation. 22, 1, p. 230-244 15 p.Research output: Contribution to journal › Article › peer-review
• COVID-19-Related Submission Priorities from the Journal of the Pediatric Infectious Diseases Society
  January 1, 2022
  COVID-19-Related Submission Priorities from the Journal of the Pediatric Infectious Diseases SocietyGreen, M., Adler-Shohet, F. C., Blyth, C. C., Chiotos, K., Gerber, J. S., Jhaveri, R., Kociolek, L., Martin-Blais, R., Palazzi, D., Shane, A. L., Schuster, J. E., Shulman, S. T., Storch, G. A., Weinberg, G. A. & Zaoutis, T., Jan 1 2022, In: Journal of the Pediatric Infectious Diseases Society. 11, 1, p. 1-2 2 p.Research output: Contribution to journal › Comment/debate
• Association between early respiratory viral infections and structural lung disease in infants with cystic fibrosis
  January 1, 2022
  Association between early respiratory viral infections and structural lung disease in infants with cystic fibrosisSanders, D. B., Deschamp, A. R., Hatch, J. E., Slaven, J. E., Gebregziabher, N., Corput, M. K. V. D., Tiddens, H. A. W. M., Rosenow, T., Storch, G. A., Hall, G. L., Stick, S. M., Ranganathan, S., Ferkol, T. W. & Davis, S. D., 2022, (Accepted/In press) In: Journal of Cystic Fibrosis.Research output: Contribution to journal › Article › peer-review