Storch Lab
Gregory A. Storch, MD
My research interests relate to the molecular diagnosis of infectious diseases. Within our diagnostic virology laboratory, we have developed molecular tests for the detection of multiple infectious disease agents, including all known human herpes viruses, polyoma viruses JC and BK, parvovirus B19, enteroviruses, HIV, Toxoplasma gondii, Bordetella pertussis and parapertussis, Ehrlichia, Rickettsia, Bartonella, Leptospira, Borrelia, Mycoplasma pneumoniae, and Chlamydia pneumoniae. Development of quantitative assays is an area of special interest, and quantitative assays for CMV, EBV, HHV-6, and BK virus have been developed. We have also implemented commercial tests for HIV RNA, hepatitis C RNA, hepatitis C genotyping, hepatitis B DNA, and have developed molecular tests for the detection of resistance of human cytomegalovirus and hepatitis B virus to antiviral drugs. Finally, we have also developed tests to detect specific forms of bacterial antibiotic resistance to antibiotics including methicillin, the fluoroquinolones, and the macrolides. This effort also includes assays to characterize the SCCmec cassette of MRSA strains and to detect the presence of the Panton-Valentine leukocidin.
Resources
Principal investigator
Gregory A. Storch, MD
Ruth L. Siteman Professor of Pediatrics
Medical Director, Project ARK
- Phone: 314-454-6050
Recent publications
- The Post-transplant Lymphoproliferative Disorders – Metagenomic Shotgun Microbial Sequencing (PTLD-MSMS) Study Methods and ProtocolDharnidharka, V. R., Wylie, K. M., Wylie, T. N., Ruzinova, M. B., Goss, C. W., Storch, G. A., Mehta-Shah, N., Byers, D., Walther, L., Jaza, L., Gu, H., Agarwal, M., Green, M., Moore, E., Swerdlow, S. H., Silveira, F., Marks, L. J., Gratzinger, D., Bagg, A. & Law, S. C. & 1 others, Gandhi, M., Oct 28 2024, In: Transplantation Direct. 10, 11, p. e1723Research output: Contribution to journal › Article › peer-review
- Azithromycin therapy in infants hospitalized for respiratory syncytial virus bronchiolitis: Airway matrix metalloproteinase-9 levels and subsequent recurrent wheezeBeigelman, A., Goss, C. W., Wang, J., Srinivasan, M., Boomer, J., Zhou, Y., Bram, S., Casper, T. J., Coverstone, A. M., Kanchongkittiphon, W., Kuklinski, C., Storch, G. A., Schechtman, K. B., Castro, M. & Bacharier, L. B., May 2024, In: Annals of Allergy, Asthma and Immunology. 132, 5, p. 623-629 7 p.Research output: Contribution to journal › Article › peer-review
- Oral Valganciclovir Initiated Beyond 1 Month of Age as Treatment of Sensorineural Hearing Loss Caused by Congenital Cytomegalovirus Infection: A Randomized Clinical TrialCollaborative Antiviral Study Group (CASG), May 2024, In: Journal of Pediatrics. 268, 113934.Research output: Contribution to journal › Article › peer-review
- Viral DNAemia and DNA Virus Seropositivity and Mortality in Pediatric SepsisCabler, S. S., Storch, G. A., Weinberg, J. B., Walton, A. H., Brengel-Pesce, K., Aldewereld, Z., Banks, R. K., Cheynet, V., Reeder, R., Holubkov, R., Berg, R. A., Wessel, D., Pollack, M. M., Meert, K., Hall, M., Newth, C., Lin, J. C., Cornell, T., Harrison, R. E. & Dean, J. M. & 1 others, Carcillo, J. A., Feb 26 2024, In: JAMA Network Open. 7, 2, p. E240383Research output: Contribution to journal › Article › peer-review
- Plasmon-Enhanced Digital Fluoroimmunoassay for Subfemtomolar Detection of Protein BiomarkersSeth, A., Liu, Y., Gupta, R., Wang, Z., Mittal, E., Kolla, S., Rathi, P., Gupta, P., Parikh, B. A., Genin, G. M., Gandra, S., Storch, G. A., Philips, J. A., George, I. A. & Singamaneni, S., Jan 10 2024, In: Nano Letters. 24, 1, p. 229-237 9 p.Research output: Contribution to journal › Article › peer-review